PROGRAM
9:50-10:00 Opening Remarks
 Hiroyuki Aburatani
10:00-12:00 Session 1: Genomic Medicine (Chair: Yoichiro Kamatani)
(10:00-10:40) "Long-read sequencing of disease-associated repeat expansions"
 Shinichi Morishita (The University of Tokyo)
(10:40-11:20) "The 100,000 genomes project and beyond: mainstreaming genome medicine in the UK National Health Service as a model for use of patient data for both clinical care and research"
 Tim Hubbard (King's College London)
(11:20-12:00) "Sequencing and Analysis of 100,000s of Human Genomes"
 Goncalo Abecasis (Regeneron)
12:00-13:00 Special Session: Data Sharing (Moderator: Tohru Masui)
 Tim Hubbard   Shinichi Morishita
 Goncalo Abecasis Yoichiro Kamatani
13:00-14:30 Lunch & Poster Session (2F: Exhibition Hall)
Meet the Expert (1F: Meeting Room 101-103)
14:30-15:30 Technology Presentation (Facilitator: Yutaka Suzuki)
 TOMY DIGTAL BIOLOGY CO., LTD.
 Oxford Nanopore Technologies
15:30-16:00 Coffee Break & Poster Session (2F: Exhibition Hall)
16:00-18:00 Session 2: Genome Regulation (Chair: Yutaka Suzuki)
(16:00-16:40) "Hierarchical genomics to interpret genome variation and dissect disease architecture"
 Emmanouil (Manolis) Dermitzakis (University of Geneva)
(16:40-17:20) "From genomics to therapeutics: dissection and manipulation of human disease circuitry at single-cell resolution"
 Manolis Kellis (MIT)
(17:20-18:00) "Evolving brains with new genes; Human-specific gene NOTCH2NL expands neuronal number in the cerebral cortex"
 Ikuo Suzuki (The University of Tokyo)
9:30-10:30 Plenary: Cancer Genomics (Chair: Hiroyuki Aburatani)
"An Immunogenomic View of Personalized Cancer Medicine"
 Thomas Hudson (AbbVie Inc.)
10:30-11:50 Session 3: Chromatin(Chair: Shinichi Morishita)
(10:30-11:10) "A 3D Code in the Human Genome"
 Erez Lieberman Aiden (Baylor College of Medicine)
(11:10-11:50) "Dynamic reorganization of three-dimensional chromosome architecture revealed by single-cell Hi-C"
 Takashi Nagano (Osaka University)
11:50-12:30 Short Talk (1)
Ryuichiro Nakato (The University of Tokyo)
Ayako Suzuki (The University of Tokyo)
12:30-14:00 Lunch & Poster Session (2F: Exhibition Hall)
Meet the Expert (1F: Meeting Room 101-103)
14:00-15:30 Technology Presentation (Facilitator: Naomichi Matsumoto)
 TWIST Bioscience
 Agilent Technology
 Scrum Inc. / 10x Genomics
15:30-16:00 Coffee Break & Poster Session (2F: Exhibition Hall)
16:00-18:00 Session 4: Single Cell (Chair: Piero Carninci)
(16:00-16:40) "Spatial genomics: transcriptome profiling in situ"
 Long Cai (California Institute of Technology)
(16:40-17:20)"Landscape of the breast cancer microenvironment at single-cell resolution"
 Alex Swarbrick (Garvan Institute of Medical Research)
(17:20-18:00) "DNA barcode technologies to dissect heterogeneous biological systems"
 Nozomu Yachie (The University of Tokyo)
9:30-10:00 Memorial Talk (Chair: Sumio Sugano)
"Sydney Brenner in memory"
 Yoshiyuki Sakaki
10:00-10:40 Short Talk (2) (Chair: Takashi Ito)
Yasuyuki Ohkawa (Kyushu University)
Saumya Agrawal (RIKEN IMS)
10:40-12:00 Session 5: New Technology (Chair: Takashi Ito)
(10:40-11:20) "Using nanopore sequencing to interrogate the genome, epigenome and transcriptome"
 Winston Timp (Johns Hopkins University)
(11:20-12:00) "Oxford Nanopore sequencing, latest updates and future development plan"
 Monolina Binny (Oxford Nanopore Technologies)
12:00-13:30 Lunch & Poster Session (2F: Exhibition Hall)
Meet the Expert (1F: Meeting Room 101-103)
13:30-14:30 Technology Presentation (Facilitator: Tatsuhiro Shibata)
 Hitachi High-Technologies Corporation
 Illumina K. K.
14:30-15:00 Coffee Break & Poster Session (2F: Exhibition Hall)
15:00-17:00 Session 6: Genome Editing (Chair: Nozomu Yachie)
(15:00-15:40) "Genome editing approaches for oncology discovery and immune engineering"
 Sidi Chen (Yale University)
(15:40-16:20) "Development of High-Throughput Functional Genomics Tools to Study Drug Interactions and Mechanisms of Cellular Uptake"
 Michael C. Bassik (Stanford University)
(16:20-17:00) "Molecular mechanism of CRISPR and structure-based development of genome editing tool towards medical applications"
 Osamu Nureki (The University of Tokyo)
17:00-17:20 Poster Award
 Naomichi Matsumoto (Yokohama City University)
17:20-17:30 Closing Remarks
 Takashi Ito (Kyushu University)
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